Targeted Drug Delivery / Smart Drug Delivery / Drug Targeting
Seyed Ali Naghi Ahmadi; Tahere Fanaei Sheykhol-Eslami; Mehri Mehrjoo; Morteza Maleki
Volume 7, Issue 4 , June 2013, , Pages 351-360
Abstract
A secure self-biased remote controller for a drug delivery system, working at 956 MHz, is designed using piezoelectric substrate containing an implantable micropump. For this purpose, the effect of Lithium Niobate substrate on the actuation voltage, signal to noise ratio, insertion loss, bandwidth, and ...
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A secure self-biased remote controller for a drug delivery system, working at 956 MHz, is designed using piezoelectric substrate containing an implantable micropump. For this purpose, the effect of Lithium Niobate substrate on the actuation voltage, signal to noise ratio, insertion loss, bandwidth, and real and imaginary part of the admittance are investigated. The results of analytical calculation and numerical simulation show that the actuation voltage of the Lithium Niobate substrate is about 5.8 V, and the calculated bandwidth is 160 MHz with the signal to noise ratio of 26.52 dB. The security for actuation of the device is assured with Barker code. The insertion loss is equal to 2.1 dB which is adequate for maximum power transfer. Numerical simulation indicates that the generated voltage could create a displacement about 9.3353 nm in the conductive diaphragm, which is enough to ascertain the correct drug delivery by the micropomp. According to the analytical calculations and numerical simulations, the performance of the designed controller is qualified to correctly stimulate the drug delivery device.
